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Material and Methods Among 28 slim customers, 15 had been treated with genital ring plus metformin and 13 women with just vaginal band. The results were examined after six months. The clients had been submitted to evaluation of lipid and carbohydrate metabolic rate; Doppler evaluation of ophthalmic artery; brachial artery flow-mediated vasodilatation; and oral sugar tolerance test. Outcomes After 6 months, the fasting insulin, glucose/insulin proportion, and homeostatic model evaluation