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Therefore, individualized therapy based on advanced analytical methods and TDM theory is of great practical significance.Compelling evidence has shown that parental experiences and age at conception may potentially shape the future health of the next generation(s). Certain factors may affect both the female and, strikingly, the male gametes potentially causing the transmission of acquired traits, which was strongly defended by Jean-Baptiste Lamarck. Neurodevelopmental psychiatric disorders, trinucleotide repeat-associated diseases, card