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Multivariate logistic regression showed that patients with high lactic acid, coagulation dysfunction, high levels of PCT, CRP, IL-6, TNF-α, CK-MB, and cTnI, but low H19 expression had an increased risk of sepsis. Peripheral blood H19 may be used for early diagnosis, clinical assessment, and prognosis of sepsis. Peripheral blood H19 may be used for early diagnosis, clinical assessment, and prognosis of sepsis. This study was designed to explore the feasibility and effectiveness of patient-centered care (PCC) on basis of guidelines of Jo