https://www.selleckchem.com/pr....oducts/pkc-theta-inh
559)) and 67% (hazard ratio=1.667 95% confidence interval=(1.501-1.85) higher risk of depression in the rheumatoid arthritis and inflammatory bowel disease cohorts, respectively. In the inflammatory bowel disease cohort, we find the risk of depression is increased for up to five years of thiopurine exposure. CONCLUSION These results provide evidence that Rac1 regulation is a viable therapeutic target for depression. Further research into therapeutics targeting Rac1 for the treatment of depression is warranted.BACKGROUND Th
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