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sed a slice thickness of less then 1 mm and steady-state sequences with diffusion-weighted imaging. Comparing the diagnostic efficacy of diffusion kurtosis imaging (DKI) derived from different region of interest (ROI) methods in tumor parenchyma for grading and predicting IDH-1 mutation and 1p19q co-deletion status of glioma patients and correlating with their survival data. Sixty-six patients (29 females; median age, 45years) with pathologically proved gliomas (low-grade gliomas, 36; high-grade gliomas, 3 were prospectively included,