https://www.selleckchem.com/pr....oducts/gusacitinib.h
The NLRP3 inflammasome is an important player in innate immunity and pathogenic inflammation. Numerous studies have implicated it in sensing endogenous danger signals, yet the precise mechanisms remain unknown. Here, we review the current knowledge on the organismal and cellular metabolic triggers engaging NLRP3, and the mechanisms involved in integrating the diverse signals. Acute respiratory infections (ARIs) are among the most common human illnesses globally. Previous studies that examined the associations between climate variabi
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