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Similar results were obtained in the evaluation using the Mexameter. After 12weeks, the melanin index of the pigmented spots significantly decreased, and it was significantly higher than that in the placebo group. There was no significant change in the erythema index. In the image analysis, there were no significant differences in skin color brightness and evenness in the active group compared with those in the placebo group. Melasolv can be effective used for skin brightening. Melasolv™ can be effective used for skin brightening. Severe

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