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Internal hydration of the ions appears to be necessary in order to achieve this separation, which will likely occur at larger cluster sizes.Statistical significance tests are a common feature in quantitative proteomics workflows. The Student's t-test is widely used to compute the statistical significance of a protein's change between two groups of samples. However, the t-test's null hypothesis asserts that the difference in means between two groups is exactly zero, often marking small but uninteresting fold-changes as statistically signi