https://www.selleckchem.com/products/nd646.html
Results In anesthetized rats, single intracorneal injection resulted, after 30 min, in respectively 300 ng/mg and 260 ng/mg cornea concentrations, dropping to low levels within hours, while staying low in plasma. The effect of hourly posaconazole eye drops resulted in 10 ng/mg cornea concentration, which was maintained with instillations every 2 and then every 4 hours.Conclusion Our results show that there is little interest of intrastromal triazole administration due to the short duration of high cornea concentrations obtaine
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