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1% of individuals with osteoarthritis and 7.7% of those without osteoarthritis had suffered at least one fracture (log-rank P-value0.001). There was a positive and significant association between osteoarthritis and fracture in the overall sample [hazard ratio (HR)=1.55, 95% confidence interval (CI)=1.50-1.60]. These findings were corroborated in all sex, age, and osteoarthritis joint site subgroups. Intervention is urgently needed to reduce the risk of fracture in adults with osteoarthritis, and further research is warranted in order to gain more of an