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Treatment of Add Treatment of add usually involves medication and psychosocial treatments. ADHD medications can include stimulants like methylphenidate or amphetamines, in addition to nonstimulants such as bupropion (Wellbutrin), atomoxetine and tricyclic antidepressants. For comorbid mood instability, mood-stabilizing drugs like clonidine (Catapres) and guanfacine(Kappvay) could be prescribed. Stimulants Stimulants are drugs that affect the central nervous system to improve alertness and energy. They could be prescribed drugs, such as amphetamines or dextroamphe