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The outcomes revealed that DHM significantly increased the cellular viability (P less then 0.01), the intracellular GSH level (P less then 0.01) and decreased the intracellular ROS level (P less then 0.01), the release of TNF-α, IL-8 (P less then 0.01) plus the apoptotic mobile percentages (P less then 0.01) in IPEC-J2 cells contrasted to that in the DON group. Metabolomic analysis uncovered that DHM restored the disorder of metabolic pathways such as for example glutamate metabolic proces