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096). We also found that both subgroups shared a spectrum of 9 alterations in 8 genes (CYP1B1 p.N453S, BAP1 p.C39fs, PIK3CA p.I391M, CDKAL1 c.1226_1227TG, POLE p.V1161fs, OCA2 p.R419Q, OCA2 p.R305W, MC1R p.V60L, MGMT p.L115F), which suggested that these genes may play a role in melanoma development. Conclusions In conclusion, despite the small cohort of patients, we found that germline mutations, such as those of PIK3CAand CYP1B1, might contribute to the differential development of SPM and MPM.Purpose Benign endobronchial tumors are ra
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