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001). No patients had progression of collapse of the femoral condyles at the final follow-up. At the final follow-up, the onset of minimal osteoarthritis was seen in two knees, with a Kellgren-Lawrence grade 1. Medulloscopy-assisted bone grafting can be an effective treatment option for early symptomatic osteonecrosis of knee following treatment for adolescent leukemia. Medulloscopy-assisted bone grafting can be an effective treatment option for early symptomatic osteonecrosis of knee following treatment for adolescent leukemia. Osteoar