https://www.selleckchem.com/pr....oducts/eidd-2801.htm
Research ethics oversight systems have traditionally emphasized the informed consent process as the primary means by which to demonstrate respect for prospective subjects. Yet how researchers can best fulfill the ethical obligations of respect for persons in pragmatic clinical trials (PCTs)-particularly those that may alter or waive informed consent-remains unknown. We propose eight dimensions of demonstrating respect in PCTs (1) engaging patients and communities in research design and execution, (2) promoting transparency and open co