https://www.selleckchem.com/products/escin.html
AIM Glucagon-like peptide-1 (GLP1) produces pleiotropic effects binding to the GLP1 receptor (GLP1-R) potentiating insulin secretion in the pancreas. GLP1-R is expressed in peripheral tissues and evidence for its role in reproduction came from knockout mice, although the relationship between GLP1 and male fertility needs to be clarified. Given that human sperm is an insulin-sensitive and insulin-secreting cell, we hypothesized that GLP-1/GLP1-R axis may be expressed and functional in these cells. RESULTS and discussion We evidenced GLP1-R