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To compare the size of the coagulation (CZ) and periablational (PZ) zones created with two commercially available devices in clinical use for radiofrequency (RFA) and microwave ablation (MWA), respectively. Computer models were used to simulate RFA with a 3-cm Cool-tip applicator and MWA with an Amica-Gen applicator. The Arrhenius model was used to compute the damage index ( ). CZ was considered when 4.6 (99% of damaged cells). Regions with 0.6 2.1 were considered as the PZ (tissue that has undergone moderate sub-abl