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6% [29/32] vs. 70.7% [94/133]; p=0.02). There was no significant difference in the frequency of exchange transfusions (ETs) between the two groups (15.6% [5/32] vs. 17.3% [23/133]; p=0.82). Compared to alloimmunized pregnancies with anti-RhD alone, pregnancies with anti-RhD in combination with anti-RhC or anti-RhE have an increased requirement for antenatal IUTs and postnatal top-up transfusions but do not have an increased need for ETs. Compared to alloimmunized pregnancies with anti-RhD alone, pregnancies with anti-RhD in combination