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From all the participants who use traditional medicine, 41 (28.3%) encountered minor adverse effects. Conclusions The study participants in Debre Tabor have good knowledge but poor attitude and utilization of traditional medicine. Copyright © 2020 Tezera Jemere Aragaw et al.Purpose The current study aims to examine the effects of advanced glycation end products (AGEs) on the microRNA (miRNA) expression profile in the kidney tissues of rats. Methods Wistar rats were randomly divided into three equal experiment groups the AGE group, the R