https://www.selleckchem.com/pr....oducts/pacap-1-38.ht
The TOPCAT investigators highlight important concerns about heterogeneity in RCT samples and how that may impactour interpretation of the results. If we are to maintain rigor in the RCT methodology and preserve its status as a reliable form of evidence for clinical practice, we must carefully consider when it is appropriate to deviate from a protocol when analyzing and interpreting trial data. The TOPCAT investigators highlight important concerns about heterogeneity in RCT samples and how that may impact our interpretation of the res