https://www.selleckchem.com/pr....oducts/bobcat339.htm
Consuming green tea has many health benefits, including regulating bone metabolism and ameliorating osteoporosis, mainly in older and postmenopausal women. This osteoprotective effect has been attributed to the biologically active polyphenol (-)-epigallocatechin-3-gallate (EGCG). Although EGCG inhibits osteoclastogenesis, its underlying molecular mechanism remains to be elucidated. Interaction between receptor activator of nuclear factor (NF)-κB ligand (RANKL) and RANK plays critical roles in the differentiation and activation of oste