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Currently, little is known about the host pathogen interaction between Phytophthora and citrus roots versus leaves. Therefore, we compared the molecular events occurring in citrus roots and leaves after zoospore inoculation with Phytophthora nicotianae (P.n.). We analyzed the physical characters and genetic responses to P.n. infection of leaves and roots for susceptible and tolerant citrus rootstocks to examine the potential for leaves to model root responses to P.n. infection. Leaves responded faster and stronger to P.n. infection than