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y/activity in conjunction with availability of in vivo carcinogenicity data revealed regions of either data-poor (hydroxylated-PAHs) or data-rich (unsubstituted, parent PAHs) PACs. These regions offer potential targets for prioritization of further in vivo assessment and for chemical read-across efforts. The analysis results are searchable through an interactive web application (https//ntp.niehs.nih.gov/go/pacs_tableau), allowing for alternative hypothesis generation.The interaction of polysaccharides with water has a critical impact on t