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The objective of this review is to identify, appraise, and synthesize available evidence related to the lived experiences of families with an adult community-dwelling person who uses drugs. The stigma experience of persons who use drugs is documented in the literature, yet little is known about the families' lived experience with a loved one who uses drugs. While often identified as an important adjunct to treatment, evidence regarding the families' lived experiences relevant to their psychosocial, physical, mental, and family health nee