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, but the number of motion states may significantly alter some quantitative parameters. © 2020 Institute of Physics and Engineering in Medicine.Upgrading the productivity of nanoparticles (NPs), generated by pulsed laser ablation in liquid (PLAL), still remains challenging. Here a novel variant of PLAL was developed, where a doubled frequency NdYAG laser beam (532 nm, ~ 5 ns, 10 Hz) at different fluences and for different times was directed into a sealed vessel, toward the interface of the meniscus of ethanol with a tilted bulk metal target. Palladi