https://www.selleckchem.com/products/mk-8719.html
OBJECTIVES Immune activation, among other driven by IFN-α and -γ activation is a main feature of progressive HIV infection. Suppressor of cytokine signaling (SOCS) 1 and 3 are negative feedback regulators of the IFN-α and -γ axis. Here, we analyzed the role of 9 single nucleotide polymorphisms (SNPs) within SOCS-1 and 3 genes for their association with HIV progression rate in a cohort of 318 rapid vs 376 slow progressors from the Swiss HIV Cohort Study. DESIGN AND METHODS We analyzed 9 SNPs, which we have identified in Swiss blood donor
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