https://www.selleckchem.com/pr....oducts/bgj398-nvp-bg
The substituent effects on the determined kinase inhibitory properties of cdk1, cdk2, Fyn, JNK3 and gsk-3β are discussed. Various 3-substitutions were found most sensitive for the protein kinase inhibition depending on the length, nature and a substituent positioning within. We identified compounds as inhibitors of several kinases as a tool to potentially combat the disease progress in a multitargeting approach. Various 3-substitutions were found most sensitive for the protein kinase inhibition depending on the length, nature