https://microrna21.com/the-int....roduction-of-a-new-f
Deletion of a cAMP-responsive CRE within the Per1 promoter blunted light-induced Per1 expression when you look at the SCN at night, while deletion of an ATF4 (CREB-2)-associated CRE into the Per2 promoter had no influence on its appearance. These outcomes proposed that the CRE into the Per1 promoter works well with light induction although not CRE in the Per2 promoter. Behavioral rhythms observed under some light problems are not suffering from the CRE-deletion in Per1 promoter, recommending

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