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An attractive hypothesis raised by our data is that increased DNA methylation may contribute to the efficiency of alternative splicing. Together, our results provide intriguing insights into the associations between gene expression, alternative splicing, and DNA methylation that may shape transcriptome complexity and proteome specificity in developing soybean nodules.Invited for this month's cover is the group of Prof. Kenneth Kam-Wing Lo at City University of Hong Kong, Hong Kong, P. R. China. The cover picture shows the selective lan