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To explore whether microRNA-21-5p (miR-21-5p) has the effect of anti-apoptosis of human alveolar type II epithelial cells (AT II). AT II cells derived from the human were cultured in vitro and used for experiments when the cells were grown until the presence of lamellar bodies and microvilli were observed by light microscope. The cells were divided into blank control group (direct culture), hydrogen peroxide (H O ) injury group (cultured with 0.5 mmol/L H O ), and miR-21-5p overexpression group (using miR-21-5p with a multiplicity of in