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[This corrects the article DOI 10.1016/j.heliyon.2020.e03900.]. Artemether-Lumefantrine (A-L) remains the drug of choice for the treatment of uncomplicated malaria in Ghana. However, the pharmaco-activity of A-L has not been assessed on various and genes. Therefore, this study sought to determine the therapeutic efficacy of A-L on parasites isolated from Ghana. The clinical study was done in Ga West Municipality, Ghana, where 78 uncomplicated malaria patients were recruited with prior consent. The patients were treated orally with A-L