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Peanut and tree nut allergies are the most important causes of anaphylaxis. Co-reactivity to more than one nut is frequent, and co-sensitization in the absence of clinical data is often obtained. Confirmatory oral food challenges (OFCs) are inconsistently performed. To investigate the utility of the basophil activation test (BAT) in diagnosing peanut and tree nut allergies. The Markers Of Nut Allergy Study (MONAS) prospectively enrolled patients aged 0.5-17years with confirmed peanut and/or tree nut (almond, cashew, hazelnut, pistachio,