https://www.selleckchem.com/pr....oducts/dl-alanine.ht
Compared with baseline, longitudinal analysis unveiled significant repertoire restrictions upon relapse (P = 0·0437) while productive TCR repertoire clonality proved to be a useful indicator of both overall and progression-free-survival [OS P = 0·0001; hazard ratio (HR) 6·220; confidence interval (CI) 2·263-11·78; PFS P = 0·0025; HR 3·086; CI 1·555-7·030]. Multivariate analysis confirmed its independence from established prognosticators, including age at diagnosis and comorbidities. Our findings establish the clinical relevance of th
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