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These six flavonoids from two subclasses disclosed the next anti-oxidant capability P EC, EGC EC, Q T, Q R. Our outcomes suggest that (1) the pyrogallol, dimerization, and C2=C3 dual bonds of flavonoids enhanced anti-oxidant activity and (2) the C3 glycosylation of flavonoids attenuated antioxidant capacity.Protein kinase type C-ε (PKCε) plays important functions in the sensitization of primary afferent nociceptors, such as for instance ion channel phosphorylation, that i