https://www.selleckchem.com/pr....oducts/ulixertinib-b
Here, the extracted γ-secretase from Alzheimer's disease (AD) brains generates amount of Aβ1-42 and Aβ1-43 compared with cognitively normal brains. This refractory γ-secretase localized in detergent-solubilized fractions from brain cortices. But activity modulated γ-secretase, which decreases Aβ1-42 and Aβ1-43 in the CSF, localized in detergent-insoluble fractions. These γ-secretase drastic alterations reflect Aβ situation in AD brains. Lung adenocarcinoma (LUAD) is a malignant tumor with poor patient survival and
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