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Centered on many medical magazines, the advantages of utilizing a larger diversity of types in neuroscience and also the drawbacks of targeting mice and rats are provided. Metabotropic glutamate receptor 5 (mGluR5) is reported to subscribe to inflammatory pain. The intracellular C-terminal domain has a Homer-binding motif that can develop an mGluR5/Homer complex. Phosphorylation of mGluR5 at the Homer binding domain improves the mGluR5/Homer interaction and modulates intr