https://pgc1signal.com/index.p....hp/application-of-is
Weighed against intervention at the transcriptional amount, focusing on the degradation procedure is apparently a more rapid and direct method. Proteasomal proteolysis and lysosomal proteolysis would be the most critical quality-control systems responsible for the degradation of proteins or organelles. Although proteasomal and lysosomal inhibitors (age.g., bortezomib and chloroquine) have actually achieved particular improvements in a few clinical application