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Methods CD34+ cells through the bone marrow of 53 MDS clients had been counted by movement cytometry and separated by magnetized bead sorting. Shh, Smo, Ptch-1 and Gli-1 (involved in Shh path) in CD34+ cells had been examined by RT-qPCR. Besides, the partnership between Shh pathway-related genetics additionally the clinical features or prognosis of MDS had been analyzed. Further, the results of jervine on MUTZ-1 cells regarding their particular expansion, a