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OBJECTIVE To explore the potential correlation between heat shock protein 60 (HSP6 gene polymorphisms and susceptibility to atherosclerosis. PATIENTS AND METHODS A total of 160 atherosclerosis patients treated in our hospital from February 2017 to February 2019 were randomly enrolled as case group, and 200 healthy adults receiving physical examination were selected as control group at the same period. Venous blood was drawn from all subjects to extract deoxyribonucleic acid (DNA). TaqMan probe technology was employed to genotype two lo