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To determine the yield of prenatal testing and screening options after identification of fetal structural abnormalities using a novel mathematical model. A retrospective chart review was conducted to collect structural abnormality and genetic testing data on infants who were evaluated postnatally by a medical geneticist. A novel mathematical model was used to determine and compare the predicted diagnostic yields of prenatal testing and screening options. Over a quarter of patients with at least one structural abnormality (28.1%, n = 222)
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