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In Chile, the tobacco tax collection does not fully cover the direct healthcare costs attributed to smoking. Despite a reduction observed on smoking prevalence between 2010 (40.6%) and 2017 (33.3%), this study shows that the burden of disease, and the economic toll due to smoking, remain high. As we demonstrate, a rise in the price of cigarettes could lead to a significant reduction of this burden, averting deaths and disability, and reducing healthcare spending. Despite a reduction observed on smoking prevalence between 2010 (40.6%) an
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