https://www.selleckchem.com/pr....oducts/PHA-739358(Da
The intervertebral disc (IVD) is made up of the annulus fibrosus (AF) and the nucleus pulposus (NP)-an inert hydrated complex. The ability of the IVD to deform is correlated to that of the NP and depends on its hydration. As the IVD ages, its hydration decreases along with its ability to deform. In adolescent idiopathic scoliosis, one of the etiological hypotheses pertains to the IVD, thus making its condition relevant for the diagnosis and monitoring of this pathology. IVD hydration depends on sex, age and spine level in
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