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Objectives Cocoon immunisation strategies involve administration of Bordetella pertussis containing vaccines to parents and family members who are in close contact with newborns. The objective of this systematic review was to evaluate the effectiveness of strategies to increase uptake of vaccination against Bordetella pertussis infection by parents and family caregivers of newborn children ( less then 3 months of age). Design A protocol driven systematic review was conducted between 2005 and February 2020. CINAHL, Medline, and Google Sch