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6 ± 1.7 and 6.1 ± 3.1 mm, respectively. The most prevalent microorganisms were Aggregatibacter actinomycetemcomitans (32.5%) and Porphyromonas gingivalis (18.6%). The patients from rural areas showed a higher percentage of A. actinomycetemcomitans (urban 17.9% vs. rural 48.9%, p=0.0018). In patients with periodontitis, the frequency of EBV, HSV1 and 2, and HCMV genes was 2.3%. Periodontitis patients had higher levels of MDA (P 2.1 ± 1.5; C 0.46 ± 0.3 μmol/g protein; p=0.0001) and total antioxidant capacity (P 0.32 ± 0.2; C 0.15 ± 0.