https://www.selleckchem.com/pr....oducts/chir-99021-ct
An amendment to this paper has been published and can be accessed via a link at the top of the paper.Myristoylation, the N-terminal modification of proteins with the fatty acid myristate, is critical for membrane targeting and cell signaling. Because cancer cells often have increased N-myristoyltransferase (NMT) expression, NMTs were proposed as anti-cancer targets. To systematically investigate this, we performed robotic cancer cell line screens and discovered a marked sensitivity of hematological cancer cell lines, incl
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