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The magnetic resonance imaging protocol included conventional sequences to determine focal lesions, and multi-shell diffusion imaging had been used with b-values of 100e lesions was related to the seriousness of infection advancement, medical disability and cognitive decline (P = 0.004, Bonferroni modification). Particularly, more and larger B-type lesions were correlated with a worse several Sclerosis Severity Score, cerebellar purpose and cognitive overall performance. H
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