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Further studies of clinical outcomes related to QBL are needed. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.OBJECTIVE This pilot study evaluated the relationship between maternal and neonatal R- and S-methadone and R- and S-2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) exposure and the severity of neonatal abstinence syndrome (NAS). The use of dried blood spots (DBS) as an alternative for plasma in assessing methadone and EDDP was also assessed. STUDY DESIGN Women receiving methadone for medicatio
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