https://fxrsignal.com/index.ph....p/put-together-inhib
This research is designed to elucidate the effect of CA IX shedding on disease cells. METHODS We generated a non-shed CA IX mutant by removal of proteins 393-402 from the stalk region and learned its phenotypic effects in comparison to full-length, shedding-competent CA IX making use of a range of assays based on immunodetection, confocal microscopy, in vitro real time cell tracking and in vivo tumour cell inoculation using xenograf