https://www.selleckchem.com/pr....oducts/melk-8a-hydro
We further identified homozygous LDB3 frameshift variants in two unrelated probands diagnosed with cardiomegaly and severely reduced left ventricular ejection fraction. Our findings demonstrate that recessive LDB3 variants can lead to an early-onset severe human phenotype of cardiomyopathy and myopathy, reminiscent of the knockout mouse phenotype, and supporting a loss of function mechanism.The COVID-19 pandemic has dramatically altered the behaviour of most of the world's population, particularly affecting the elderly, in