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05 for all). Lower CD38+ CD8+ T cells were also associated with diabetes in both groups. CONCLUSIONS The CD4+ and CD8+ T cell subsets associated with diabetes are similar in PWH and HIV-negative individuals, suggesting that diabetes in PWH may be related to chronic immune activation. © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.BACKGROUND Leprosy, cutaneous leishmaniasis (CL) and Chaga